Cartilage tissue enhances proteoglycan retention by nucleus pulposus cells in vitro
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چکیده
منابع مشابه
Cartilage tissue enhances proteoglycan retention by nucleus pulposus cells in vitro.
OBJECTIVE To investigate the effect of cartilage on nucleus pulposus (NP) tissue in an in vitro model. METHODS Cells were isolated from bovine NP or articular cartilage and allowed to form tissue in vitro. The NP tissue was grown either alone or in the presence of cartilage tissue (coculture) for up to 4 weeks and examined for histologic appearance, gene expression, and biochemical compositio...
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متن کاملConditioned medium derived from notochordal cell-rich nucleus pulposus tissue stimulates matrix production by canine nucleus pulposus cells and bone marrow-derived stromal cells.
OBJECTIVES Conditioned medium derived from notochordal cell-rich nucleus pulposus tissue (NCCM) was previously shown to have a stimulatory effect on bone marrow stromal cells (BMSCs) and nucleus pulposus cells (NPCs) individually, in mixed species in vitro cell models. The objective of the current study was to assess the stimulatory effect of NCCM on NPCs in a homologous canine in vitro model a...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2010
ISSN: 0004-3591
DOI: 10.1002/art.27651